Endocrine Abstracts

Introduction: Hemoglobin (Hb) is the main carrier and buffer of Nitric oxide. Recently, an inverse association between Hb and the endothelium dependent relaxation was observed in patients with Type 2 diabetes. Testing whether this association exists also in diabetic nephropathy is important because anemia in these patients starts at an earlier stage than in other renal disease. Also, at population level diabetes and renal dysfunction, particularly albuminuria, contribute indep...

Objective: Visfatin, a novel adipocytokine, is predominantly expressed in visceral fat and correlated with obesity. The pathophysiologic role of visfatin in metabolic syndrome (MS) is not clear. We aimed to investigate the relationship between plasma visfatin levels and components of MS, and also the effect of therapeutic lifestyle change (TLC) on these parameters.Design and methods: Nineteen patients (5 male, 14 female; mean age 51.0±9.3 years; bod...

Objective: The pleiotropic functions of statins are crucial in reducing cardiovascular events. There is controversy about their effects on insulin resistance. The aim of this study was to investigate the effect of Fluvastatin treatment on plasma adiponectin and insulin levels in a group of dyslipidemic population who had no confounding factors for insulin resistance such as diabetes or hypertension.Design and methods: Forty nine (27 male, 22 female; mean...